Emerging trends: liquid biopsy and improving survivorship
As technology evolves, life insurers should closely monitor two trends poised to shape the future of cancer insurance:
- The rise of liquid biopsy
- Improving survivorship
Liquid biopsy: a potential game-changer in cancer detection
While a traditional biopsy requires extracting tissue samples, a liquid biopsy offers a less invasive approach by analyzing bodily fluids such as blood, urine, or cerebrospinal fluid. The key innovation is its ability to detect and analyze fragments of DNA/RNA shed by cancer cells into the bloodstream or other bodily fluids.
By identifying these fragments before symptoms appear, a liquid biopsy can theoretically detect cancer at a more treatable stage. Earlier interventions could dramatically transform patient outcomes.
Healthcare providers may also gain a deeper understanding of a patient's cancer, including the presence of any remaining disease post-treatment and a potential resistance to certain therapies. They can then tailor a treatment plan and monitor a patient's progress without the need for repeated – and potentially risky – invasive biopsies.
This approach holds the potential to revolutionize screening, diagnosis, and disease tracking. It is important to note, however, that a recent study has challenged the efficacy of a widely used liquid biopsy blood test, and further research will be necessary.
For insurers, the widespread adoption of liquid biopsy technology could significantly impact cancer coverages. Currently, diagnostic capability for early-stage cancer is limited, and the high frequency of false positives increases medical costs due to excessive testing. Over time, this could result in higher claims volume, limiting product sustainability.
Liquid biopsy for precancerous lesions is currently undergoing clinical trials and may transform the diagnostic process. If fluid tests alone could one day predict the risk of developing cancer from precancerous lesions and enable early-stage treatment, it would lower healthcare costs and reduce the burden on patients. Also, the definition of cancer could expand to include lesions that have a high probability of becoming cancerous.
Increasing the number of diagnosed cases is only one factor. Earlier-stage cancer tends to have a better prognosis, leading to a larger pool of survivors. Because most cancer products in Japan provide lifetime coverage with unlimited payment, this has a significant impact on product sustainability.
The improving survivorship of cancer
With genetic and molecular information obtained from liquid biopsies, oncologists can select the most appropriate targeted therapies or immunotherapies for each patient's unique cancer profile. This precision-medicine approach could lead to more effective, tailored treatment plans and further improve survivorship.
By altering the traditional risk profile and claims patterns associated with cancer, this shift has profound implications for the insurance industry. Increased availability of advanced cancer drugs will accelerate this evolution. Private insurance policyholders who have the financial means to access advanced treatments and drugs – even those outside the public health system – will be especially affected.
In the past, cancer insurance policies in Japan often provided lump-sum payouts either at diagnosis or during the initial course of treatment. With more survivors, insurers must adapt their products and underwriting strategies to address policyholders’ evolving needs. This may include extended coverage periods, more comprehensive benefits for ongoing care, and innovative risk-management strategies.
Insights from across Asia
As insurers observe the unique challenges of the Japanese market, they can also draw lessons from nearby nations. By examining features and trends of cancer and critical illness insurance products in various markets, insurers can gain a broader understanding of the global landscape and identify opportunities for cross-pollination of best practices.
In Asian markets outside Japan, cancer is usually part of critical illness insurance, providing lump-sum payments for a range of serious conditions. Products typically include a maximum number of times to file a cancer claim, limiting the exposure to future cancer risk. For example:
- A Hong Kong multiple-pay cancer product pays 500% of the sum assured, after which the policy terminates. Expanding coverage beyond cancer while applying limits mitigates risk through diversification.
- In Korea, a move to lower payments for early-stage thyroid cancer seeks to manage a growing trend of over-diagnosis.
- Similarly in China, regulators recommend lower payments for certain cancers linked to over-diagnosis and anti-selection.
Applying the lessons from Asia
As both the insurance market and cancer risks continue to evolve, the industry must remain responsive to emerging trends. Liquid biopsy and the increased number of cancer survivors present both challenges and opportunities for insurers, requiring new products and strategies to meet the changing needs of policyholders.
By drawing insights from global markets, particularly from Japan and other Asian countries, forward-looking insurers and reinsurers can expand and transform the cancer and critical illness insurance landscape. In doing so, they can help ensure that individuals and families have access to comprehensive financial protection when they need it most.
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